Citrinin toxicity
WebCitrinin C13H14O5 CID 54680783 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. WebNov 14, 2024 · Red yeast rice is the product of yeast (Monascus purpureus) grown on white rice. The powdered yeast-rice mixture is a dietary staple in Asia and has been used in traditional Chinese medicine. Red yeast rice is also available as an oral supplement. Red yeast rice might contain compounds that appear to lower cholesterol levels.
Citrinin toxicity
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WebApr 5, 2007 · Although citrinin is one of the well-characterized mycotoxins, information on its mechanism of toxic action is limited. Clinically, citrinin was shown to cause renal disease in poultry, pigs, dogs and rats [2, 3]. The electron transport system of the kidney and liver mitochondria were considered as the target of the toxic action of citrinin . WebMay 9, 2024 · Mycotoxins are naturally occurring toxins produced by certain moulds (fungi) and can be found in food. The moulds grow on a variety of different crops and foodstuffs including cereals, nuts, spices, dried fruits, apples and coffee beans, often under warm and humid conditions. Mycotoxins can cause a variety of adverse health effects and pose a ...
WebCitrinin is considered as one of the strongest nephrotoxins to animals, and the levels of toxicity differ between species . Citrinin can act together with Ochratoxin A, interfere with RNA synthesis and suppress it in rodent kidneys ( 105 ). WebCitrinin was found to be a hepatotoxic and nephrotoxic mycotoxin. The lethal dose (LD 50) of citrinin has been reported to be about 35–58 mg kg −1 in an oral administration to a …
WebCitrinin, a nephrotoxic mycotoxin, has been of growing importance also for the "International Agency for Research on Cancer", ever since its presumable role in the occurrence of Balcan endemic nephropathy (BEN) was discussed at the congress on "Mycotoxins, Endemic Nepthropathy and Urinary Tract Tumo … Weband J zearalenols), nephrotoxic (ochratoxins, citrinin, oosporeine), dermonecrotic (trichothecenes), or immunosuppressive (aflatoxin B1, ochratoxin A, and T-2 toxin)…. Much of the published infor-mation on toxicity comes from studies in experimental animals, and these may not reflect the effects of mycotoxins on humans and other animals….
WebApr 5, 2007 · While, the citrinin treatment did not induce the genes involved in the DNA repair. Results from both microarray studies suggest that citrinin treatment induced …
WebYes. Some red yeast rice products contain a contaminant called citrinin, which is toxic and can damage the kidneys. In a 2024 analysis of 37 red yeast rice products, only one had citrinin levels below the maximum … ipod replacement battery serviceWebCitrinin appears to be toxic by multiple pathways including inhibition of nucleic acid synthesis, inhibition of microtubule assembly and tubulin polymerization, alteration of … ipod restore software download freeWebApr 30, 2024 · As common food and feed contaminants of fungal origin, the interest in the potential neurotoxicity of ochratoxin A, citrinin and their metabolites has recently increased. Primary porcine brain capillary endothelial cells were used to investigate cytotoxic or barrier-weakening effects of ochratoxin A, ochratoxin α, citrinin and dihydrocitrinone. orbit brass twin sprayWebSep 22, 2016 · Citrinin, but not ochratoxin A, toxicity is exacerbated in mutants with a defective antioxidant response or multidrug export. The indicated yeast strains were … ipod replacement screenWebMay 22, 2014 · The enhanced toxicity of citrinin in a pdr5 mutant was further confirmed by an independent assay using FDA as a live cell stain upon acute citrinin stress in potassium phosphate buffer (Figure 4C). These results indicated that Pdr5 was a major citrinin export activity in yeast and we postulated that pdr5 mutant cells were more sensitive to the ... ipod ring headphonesWebThe present investigation was conducted to evaluate the maternal toxicity of citrinin (CIT) and endosulfan administered per os either alone or in combination in pregnant rats during gestational days 6-20. CIT (group I, 10 mg kg (-1) feed, through diet) and endosulfan (group II, 1 mg kg (-1) body weight, by oral intubation) when administered ... orbit brass sprinkler head popped offWebThe role of altered mitochondrial function in citrinin-induced toxicity to rat renal proximal tubule suspensions*1 orbit bunbury equipment